According to a report by National Center for Biotechnology Information, chronic pain is a persistent pain that lingers for 3 months or more. The occurrence of chronic pain in the population is 10–15%. In individuals with chronic non-cancer pain, the commonness of opioid induced constipation varies from 41% to 81%. The common sign for opioid use in non-cancer pain is muskoskeletal pain such as degenerative joint disease, headache back pain, and fibromyalgia. In the current scenario, around 4% of adults in the U.S. undergo chronic opioid therapy.
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The Centers for Disease Control and Prevention (CDC) projected that excessive and unregulated prescription of opioids by healthcare providers is one of the key reasons for opioid-related overdoses. Around 90% of individuals suffering from moderate to severe pain are prescribed opioids.
Rising number of patients using illegal medicines and deferred use of opioids in the therapy of chronic pain are some of the key factors driving growth of the opioid induced constipation (OIC) treatment market. Moreover, it has been observed that the untapped market for advantageous, successful and safe therapeutic solutions in OIC drug is extensive and developing at a fast pace, especially in developed regions.
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Prevalence of opioid induced constipation is rising considerably. According to the American Academy of Pain Medicine (AAPM), around 100 million patients in the U.S. suffered from opioid induced constipation in 2013. Furthermore, AAPM also estimated that the number of occurrences would rise, owing to the increase in the number of individuals taking opioid drugs. There is a growing responsiveness towards the availability of a large array of opioid drugs. This will encourage the patients to resort to using these drugs to treat chronic pains.
The rising number of opioid induced constipation patients, particularly in the North America region is likely to drive the growth of the overall opioid induced constipation treatment industry. The regional market is projected to grow at a considerable rate due to the presence of large number of people who use opioid drugs. This is owing to high prevalence of disease associated with chronic pain in this region.
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Some of the major companies operating in the opioid induced constipation treatment market in the current scenario are Daewoong Co. Ltd., Takeda Pharmaceutical Company Limited, Boehringer Ingelheim, Cosmo Pharmaceuticals, AstraZeneca plc, Abbott Laboratories, Valeant Pharmaceuticals, C.B. Fleet Company, Inc., and Bayer AG.